University of California, San Diego (UCSD)

Feasibility and Efficacy of Time-Restricted Eating in Diabetes Management

Research Area
Diabetes

Grant Type
Network

Year
2021

Abstract

To develop a practical, easy to adopt, and cost-effective lifestyle intervention for patients with Type 2 Diabetes Mellitus (T2DM) that can be used alongside medications for T2DM.

Recent studies have shown that the timing of when people eat plays a large role in health, including body weight and blood sugar. Our research team has shown that time-restricted eating (TRE), which limits calories to an eating window of 10-hours per day, improves weight, blood pressure, bad cholesterol, and blood glucose levels. In addition, TRE is associated with improved quality of life measures such as improved sleep quality and has high rates of adherence. However, there has not yet been a randomized clinical trial to assess TRE in patients with T2DM that are on common diabetes medications.

Our network will leverage the expertise of research physicians and basic to examine the impact of TRE as a lifestyle intervention to improve treatment for T2DM. This research is an innovative approach that utilizes remote monitoring and guidance, wearable medical devices, and a smartphone app to deliver and promote a 10-hour TRE intervention to patients with T2DM. Based on our prior work in patients with metabolic syndrome/prediabetes, we hypothesize this intervention will improve glucose levels and cardiovascular health associated with T2DM.