2023 Annual Scientific Meeting

Meeting Info

LARRY L. HILLBLOM FOUNDATION 19th ANNUAL SCIENTIFIC SESSIONS

THE MONTEREY PLAZA HOTEL & SPA
MONTEREY, CA
OCTOBER 23 – 24, 2023

Important Deadlines:
August 4th: Registration closes – submit your online registration form prior to August 4th
August 18th: Room reservation deadline – book directly with the Monterey Plaza Hotel

For immediate questions please contact us.

Final Meeting Agenda

LARRY L. HILLBLOM 19TH ANNUAL SCIENTIFIC SESSIONS

The Monterey Plaza Hotel & Spa
400 Cannery Row
Monterey, CA
October 23 – 24, 2023

Note to Speakers: Network grants have 30 minute time slots, with 20 minutes to present and 10 minutes for Q&A from our SAB and audience. Start-Up and Fellowship grants have 15 minute time slots, with 10 minutes to present and 5 minutes for Q&A from our SAB and audience.  Please do not let your slide presentations exceed the allowed 20 minutes or 10 minutes, so that we have enough time for discussion.

MONDAY
TUESDAY

Monday, October 23rd, 2023

OVERVIEW

Registration – Monterey Bay Foyer
7:30am – 8:30am
Breakfast – Carmel Ballroom
7:30am – 8:30am
Scientific Sessions – Monterey Bay Ballroom
8:30am – 12:30 pm
Lunch – Central Plaza
12:30pm – 1:45pm
Scientific Sessions – Monterey Bay Ballroom
1:45pm – 5:00pm
Cocktail Reception – North Plaza
6:00pm – 7:00pm
Dinner – Carmel Ballroom
7:00pm – 9:00pm

SCIENTIFIC SESSIONS: NETWORK, START-UP & FELLOWSHIP GRANTS

Welcome & Opening Remarks
8:30 AM – 8:45 AM
Speaker: Peter Donnici, President

Network Grantee Presentation: UCSD; Astrocyte-to-Neuron Conversion to Replace Dead Neurons in Dementing Disorders
8:45 AM – 9:15 AM
Speaker: William Mobley, MD, PhD

Network Grantee Presentation: UCSF; T Regulatory Cell Activity and Function in Type 1 Diabetes
9:15 AM – 9:45 AM
Speaker: Mark Anderson, MD, PhD

Network Grantee Presentation: Sanford Burnham; Autophagic Control of the Epigenome in Senescence – from Mechanisms to Senolytics
9:45 AM – 10:15 AM
Speaker: Malene Hansen, PhD on behalf of Peter Adams, PhD

Network Grantee Presentation: Salk Institute; Adipose PDE4D: a New Druggable Pathway to Overcome Insulin Resistance
10:15 AM – 10:45 AM
Speaker: Ron Evans, PhD

BREAK
10:45 AM – 11:00 AM

Network Grantee Presentation: UCSF; Testing How Competition Among Mitochondrial Genomes Impacts Aging and Health
11:00 AM – 11:30 AM
Speaker: Patrick O’Farrell, MD

Network Grantee Presentation: UCSD; Time-Restricted Eating as a Lifestyle Intervention to Improve Glycemic Control and Atherogenic Lipids in Patients
11:30 AM – 12:00 PM
Speaker: Pam Taub, MD

Network Grantee Presentation:  Salk Institute; The Marmoset as a Model of Aging and of Age-Related Neurodegenerative Disease
12:00 PM – 12:30 PM
Speaker: John Reynolds, PhD and Courtney Glavis-Bloom, PhD

LUNCH
12:30 PM – 1:45 PM

Network Grantee Presentation: UCLA; Larry L. Hillblom Islet Research Center Network Grant for Beta Cell Regeneration
1:45 PM – 2:15 PM
Speaker: Peter Butler, MD

Start-Up Grantee Presentation: UCLA; Establishing Tissue-Specific Optimal Animal Models for Drug Discovery in Type 2 Diabetes
2:15 PM – 2:30 PM
Speaker: Tatyana Gurlo, PhD

Fellowship Grantee Presentation: UCLA; Live Cell Imaging of Islet Cell Metabolic Trajectory in Health and Diabetes
2:30 PM- 2:45 PM
Speaker: Zhongying Wang, PhD

Start-Up Grantee Presentation: UCLA; Neural Circuit Mechanisms of Age-Related Decline in Motor Skills
2:45 PM – 3:00 PM
Speaker: Ahmet Arac, PhD

Start-Up Grantee Presentation: UCLA; Rare Genetic Risk and Cell-Type Gene Networks in Tauopathy Across Ancestries
3:00 PM – 3:15 PM
Speaker: Timothy Chang, PhD

Start-Up Grantee Presentation: UCSF; Biological Signatures of Neurodegeneration and Aging in Postoperative Delirium
3:15 PM – 3:30 PM
Speaker: Sara LaHue, PhD

BREAK
3:30 PM – 3:45 PM

Center Grantee Presentation: Buck Institute; The Larry L. Hillblom Center for Integrative Studies of Aging
3:45 PM – 4:00 PM
Speaker: Gordon Lithgow, PhD

Fellowship Grantee Presentation: Buck Institute; The Role of Methylglyoxal(MGO)-Derived AGEs in Regulating Feeding
4:00 PM – 4:15 PM
Speaker: Muniesh Muthaiyan Shanmugam, PhD

Fellowship Grantee Presentation: Salk Institute; Delivery of Astrocyte-Secreted Factor to Rescue Synapses in Alzheimer’s Disease
4:15 PM – 4:30 PM
Speaker: Aksinya Derevyanko, PhD 

Fellowship Grantee Presentation: UC-Irvine; Influence of C5a-C5aR1 Signaling on Synaptic Pruning in Alzheimer’s Disease
4:30 PM – 4:45 PM
Speaker: Angela Gomez-Arboledas, PhD 

Fellowship Grantee Presentation: UCSF; Transcriptional Landscape of Cellular Senescence in the Human Brain in Healthy Aging and in Neurodegenerative Diseases
4:45 PM – 5:00 PM
Speaker: Adit Friedberg, PhD

BREAK
5:00 PM – 6:00 PM

RECEPTION
6:00 PM – 7:00 PM

DINNER
7:00 PM – 9:00 PM

Tuesday, October 24th, 2023

OVERVIEW

Registration – Monterey Bay Foyer
7:00am – 8:00am
Breakfast – Carmel Ballroom
7:00am – 8:00am
Scientific Sessions – Monterey Bay Ballroom
8:00am – 12:00pm
Lunch – Central Plaza
12:00pm – 1:00pm

SCIENTIFIC SESSIONS: START-UP & FELLOWSHIP GRANTS

Start-Up Grantee Presentation: UCSF; Using Genetics, CRISPR and Patient iPSC to Model C9orf72 FTD/ALS
8:00 AM – 8:15 AM
Speaker: Claire Clelland, PhD

Start-Up Grantee Presentation: UCSF; Development of a Novel T Cell Therapy to Induce Beige Adipogenesis
8:15 AM – 8:30 AM
Speaker: Sagar Bapat, PhD

Start-Up Grantee Presentation: USC; Actin-Mitochondria Interactions During Stress and Aging
8:30 AM – 8:45 AM
Speaker: Ryo Higuchi-Sanabria, PhD

Start-Up Grantee Presentation: UCSF; Mechanisms of Autoimmune Diabetes Provoked by Cancer Immunotherapy
8:45 AM – 9:00 AM
Speaker: Zoe Quandt, PhD

Start-Up Grantee Presentation: UCSD; Chemical Tools for Deciphering Parkinson’s Disease Signaling
9:00 AM – 9:15 AM
Speaker: Fleur Ferguson, PhD

Start-Up Grantee Presentation: UCSF; Neural Network Dysfunction and Inflammatory Dysregulation in Alzheimer’s Disease
9:15 AM – 9:30 AM
Speaker: Kamalini Ranasinghe, MD, PhD

Start-Up Grantee Presentation: Cedars-Sinai; Role of Cysteine String Protein in Dopamine Neuron Function and Vulnerability to Degeneration
9:30 AM – 9:45 AM
Speaker: Katlin Silm, PhD

BREAK
9:45 AM – 10:15 AM

Fellowship Grantee Presentation: UCSF; Role of Apolipoprotein E in Diet-Responsive Hypothalamic Microglial Regulation of Obesity and Metabolic Disease
10:15 AM – 10:30 AM
Speaker: Andrew Folick, MD, PhD

Fellowship Grantee Presentation: Stanford; Rejuvenating the Aging Brain — Genetic Dissection of Synaptic Adhesion Molecules on Promoting Synapse Formation
10:30 AM – 10:45 AM
Speaker: Xuchen Zhang, PhD

Fellowship Grantee Presentation: UCSF; Integrating the Metabolome with the Transcriptome and miRNAome in Underactive Adults at Risk for Type 2 Diabetes
10:45 AM – 11:00 AM
Speaker: Kimberly Lewis, PhD

Fellowship Grantee Presentation: UCSF; Uncovering Function and Regulation of an Aging-Associated Interferon-Responsive Microglial State
11:00 AM – 11:15 AM
Speaker: Amanda McQuade, PhD

Fellowship Grantee Presentation: UCSF; Elucidating the Role of Oxidative Stress and pATM Signaling in Aging and Dementia
11:15 AM – 11:30 AM
Speaker: Sarah Kaufman, PhD

Fellowship Grantee Presentation: UCSF; Screening and Characterization of Protein Folding Correctors for Non-Surgical Treatment of Corneal Endothelial Dystrophy
11:30 AM – 11:45 AM
Speaker: Finn Wolfreys, PhD

Fellowship Grantee Presentation: UCSF; Role of the Exercise Blood Factor Gpld1 in Restoring Brain Vasculature Function and Cognition in Aging
11:45 AM – 12:00 PM
Speaker: Gregor Bieri, PhD

LUNCH
12:00 PM – 1:00 PM

For specific questions related to your presentation please contact us.

Registration and Meeting Information

The Larry L. Hillblom Foundation 19th Annual Scientific Meeting will take place in Monterey, CA on October 23rd & October 24th, 2023.

Registration is open and the online “registration form” must be completed no later than Friday, August 4th, 2023.

All travel, transportation, housing and incidental meals are the responsibility of each grantee. Meeting attendance is mandatory. The LLHF includes in each of your grant budgets money for travel to attend our Annual Scientific Meeting.

The Foundation *does not* make your hotel reservation. In addition to completing the registration form, you must contact the Monterey Plaza Hotel directly to reserve your room.

Meeting presentations will begin at 8:30 a.m. on Monday, October 23rd and conclude on Tuesday, October 24th at 1:00 p.m. Please plan your travel accordingly to participate in ALL meeting activities.

HOTEL INFORMATION
TRANSPORTATION
MEALS
BUSINESS CENTER
ADDITIONAL NOTES

Hotel Information

Monterey Plaza Hotel & Spa
400 Cannery Row
Monterey, CA 93940

Main Phone: 831-920-6710
Reservations: 800-334-3999 (mention that you are with the Larry L. Hillblom Foundation Scientific Meeting)
Fax: 831-646-0285
Monterey Plaza Hotel & Spa Website

Reservations

You will need to secure your room reservation by Friday, August 18th, 2023 in order to guarantee accommodation. A credit card will be required in order to guarantee your reservation and an advance deposit will be charged to guarantee your room. All travel, transportation, housing and incidental meals are the responsibility of each grantee. Please contact the hotel directly to secure your room with our group rate.

Group Room Rate: Please book directly with the hotel as soon as possible.

The following rooms/rates that are available in our block on both Sunday and Monday nights are (you can also extend your stay at the group rate if rooms are available):

  • $279 per night plus tax – Inland View Balcony
  • $279 per night plus tax – Inland View
  • Note: Valet parking is an additional $35++ nightly fee with 24 hour in and out privileges included
  • Toll Free Reservation Number: 800-334-3999
  • Please reference the “Larry L. Hillblom Foundation Scientific Meeting” when making your reservation, so that you will receive our group rate and be added to the correct room block.

Transportation

General Airline & Airport Information / Driving Directions:

Airports:

  • Monterey Peninsula Airport (MRY) is a 10 minute drive to the hotel and has over 40 daily flights on several major airlines.
  • San Jose Airport (SJC) is 75 miles north of Monterey, with a driving time of approximately 1.5 hours.
  • San Francisco Airport (SFO) is 100 miles north of Monterey, with a driving time of approximately 2 hours.

Ground Transportation:

Meals

The following meals will be provided for you during the program:

  • Monday, October 23rd: Breakfast, Lunch and Dinner
  • Tuesday, October 24th: Breakfast and Lunch

Business Center

  • There are two 24 hour self service business centers located the hotel (charges vary).

Additional Notes

As a reminder, the LLHF includes in each of your grant budgets money for travel to attend our Annual Scientific Meeting. In addition to your required presentation, as a professional courtesy to our Board and your fellow scientists, you are expected to participate in all of the activities of our meeting.

If you have any questions regarding the scientific meeting or hotel information, please contact us directly.

We hope that you have had an exciting and productive year! We are looking forward to seeing each of you in October.

LLHF Annual Meeting Registration Form

Presentation Information

Specific Content for Presentations

  1. Please specifically address the following in your talk: research findings to date, progress over the last year, goals for the coming year or conclusions/findings and future direction.
  2. Please limit the number of slides to 1 per minute so that you won’t exceed your stated time limit.
  3. NETWORK Grantees and Co-Investigators will be allocated 20 minutes TOTAL for their presentation.
    • Please speak no longer than 20 minutes because we need to allow 10 minutes at the end of your allotted time for a few questions and discussion.
  4. START-UP and FELLOWSHIP Grantees will be allocated 10 minutes TOTAL for their presentations.
    • Please speak no longer than 10 minutes because we need to allow 5 minutes at the end of your allotted time for a few questions and discussion.
    • The presentation should be articulated clearly and concisely and should be engaging for the audience. We suggest that you practice with your mentors and get guidance and final approval from them, as the oral presentation will impact your overall review from the LLHF SAB and Board.
    • If this is your final presentation, please include a “summary” slide that encapsulates your LLHF project and discusses your future plans.  Please make sure to include bullet points that address the following: 1) where you are going, 2) any active research grants/projects that you are currently working on, 3) any pending grants/funding, 4) any published papers, 5) any awards/honors, etc.

Please keep in mind that it is not necessary to give an exhaustive discussion on your research project. Focus on a few key points or significant findings that will be important to or of interest to the audience, and allow the Moderator or audience members to ask about the issues they want to hear more about.

Technical Requirements and AV Information for Presentations

  1. An AV technician from Five Star Audio Visual will be present in the Monterey Bay Ballroom at 7:00 am on Monday, October 23rd & Tuesday, October 24th to upload your file and to review the presentation procedure with you.
  2. For continuity, ALL presentations will be loaded onto one central laptop. NO personal laptops will be used during the presentations. (AV will be able to accommodate either your PC or your Mac file format).
  3. Please bring your presentation to the AV tech via flash drive well in advance of your scheduled presentation time. Make sure to allow ample time to check your presentation once it is uploaded.
  4. Please create 1 single file for your presentation. 
  5. If you are a Network Grantee with additional presentations from your Co-Investigators, please make sure that the ENTIRE presentation is ONE file. It is the responsibility of the Network P.I. to collaborate with your team to create a single presentation file for the meeting.
  6. The title of the file should be the name of the LLHF Grantee/Principle Investigator.
  7. Please try not to include any specialized fonts, embedded video/movies or sound in your presentation. We will NOT make an exception to use your personal laptop so that you can play embedded video, etc.

We do not want you to lose your opportunity to present your research to our SAB and Board of Directors; therefore, we would appreciate your cooperation with these guidelines.

If you have any questions please contact us.